Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hoxd4  homeobox D4   (Synonyms: Hox-4.2, Hox-5.1)
Results	Reference
1*	J:68216 Akasaka T, van Lohuizen M, van der Lugt N, Mizutani-Koseki Y, Kanno M, Taniguchi M, Vidal M, Alkema M, Berns A, Koseki H, Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression. Development. 2001 May;128(9):1587-97
1*	J:73281 Allan D, Houle M, Bouchard N, Meyer BI, Gruss P, Lohnes D, RARgamma and Cdx1 Interactions in Vertebral Patterning. Dev Biol. 2001 Dec 1;240(1):46-60
1*	J:50401 Bel S, Core N, Djabali M, Kieboom K, Van der Lugt N, Alkema MJ , Van Lohuizen M, Genetic interactions and dosage effects of Polycomb group genes in mice. Development. 1998 Sep;125(18):3543-51
1*	J:64019 Bel-Vialar S, Core N, Terranova R, Goudot V, Boned A, Djabali M, Altered retinoic acid sensitivity and temporal expression of Hox genes in polycomb-M33-deficient mice. Dev Biol. 2000 Aug 15;224(2):238-49
1	J:79367 Collins EC, Appert A, Ariza-McNaughton L, Pannell R, Yamada Y, Rabbitts TH, Mouse Af9 Is a Controller of Embryo Patterning, Like Mll, Whose Human Homologue Fuses with AF9 after Chromosomal Translocation in Leukemia. Mol Cell Biol. 2002 Oct;22(20):7313-24
1*	J:41551 Dupe V, Ghyselinck NB, Wendling O, Chambon P, Mark M, Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse. Development. 1999 Nov;126(22):5051-9
1*	J:44065 Folberg A, Kovacs EN, Featherstone MS, Characterization and retinoic acid responsiveness of the murine Hoxd4 transcription unit. J Biol Chem. 1997 Nov 14;272(46):29151-7
1*	J:58620 Folberg A, Kovacs EN, Huang H, Houle M, Lohnes D, Featherstone MS, Hoxd4 and rarg interact synergistically in the specification of the cervical vertebrae. Mech Dev. 1999 Dec;89(1-2):65-74
1*	J:55390 Folberg A, Nagy Kovacs E, Luo J, Giguere V, Featherstone MS, RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid. Dev Dyn. 1999 Jun;215(2):96-107
1*	J:326160 Hintermann A, Guerreiro I, Lopez-Delisle L, Bolt CC, Gitto S, Duboule D, Beccari L, Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken. Development. 2022 Jun 15;149(12):dev200594
1	J:102844 Ishii M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE Jr, Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development. 2005 Nov;132(22):4937-50
1*	J:80934 Jiang X, Choudhary B, Merki E, Chien KR, Maxson RE, Sucov HM, Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryos. Mech Dev. 2002 Sep;117(1-2):115-22
1	J:79649 Kawazoe Y, Sekimoto T, Araki M, Takagi K, Araki K, Yamamura K, Region-specific gastrointestinal Hox code during murine embryonal gut development. Dev Growth Differ. 2002 Feb;44(1):77-84
1*	J:119875 Lebel M, Mo R, Shimamura K, Hui CC, Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
1	J:216613 Liang D, Wang X, Mittal A, Dhiman S, Hou SY, Degenhardt K, Astrof S, Mesodermal expression of integrin alpha5beta1 regulates neural crest development and cardiovascular morphogenesis. Dev Biol. 2014 Nov 15;395(2):232-44
1	J:146408 Pilon N, Oh K, Sylvestre JR, Savory JG, Lohnes D, Wnt signaling is a key mediator of Cdx1 expression in vivo. Development. 2007 Jun;134(12):2315-23
1	J:177362 Rhinn M, Schuhbaur B, Niederreither K, Dolle P, Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16687-92
1*	J:16077 Schneider-Maunoury S, Topilko P, Seitandou T, Levi G, Cohen-Tannoudji M, Pournin S, Babinet C, Charnay P, Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell. 1993 Dec 17;75(6):1199-214
1*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1	J:109102 Terranova R, Agherbi H, Boned A, Meresse S, Djabali M, Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6629-34
1*	J:75947 van den Akker E, Forlani S, Chawengsaksophak K, de Graaff W, Beck F, Meyer BI, Deschamps J, Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation. Development. 2002 May;129(9):2181-93
1	J:54222 Xu X, Li C, Takahashi K, Slavkin HC, Shum L, Deng CX, Murine fibroblast growth factor receptor 1alpha isoforms mediate node regression and are essential for posterior mesoderm development. Dev Biol. 1999 Apr 15;208(2):293-306
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48